Two drama CDs were created for the series, as well as a twenty-six episode anime adaptation. Produced by Studio Deen, the anime series' first season aired in Japan on TV Tokyo between April 8, 2008 and July 1, 2008. The second season, titled Vampire Knight Guilty aired on the same station from October 7, 2008 and December 30, 2008. The anime uses many of the same voice actors as were used for the drama CDs. The anime adaptations have been licensed for release in North America by Viz Media.
Yuki Cross's earliest memory is of a snowy night in winter, when she was attacked by one vampire and was saved by another, Kaname Kuran. Yuki is the adopted daughter of the Headmaster of Cross Academy, Kaien Cross, who is an ex-vampire hunter that now wishes for vampires and humans to live alongside peacefully. She has grown up and become a prefect for the school with one main purpose: for vampires to coexist peacefully with humans. Her fellow guardian, Zero Kiryu, a childhood companion whose parents were killed by a pure-blood vampire, is now determined to kill them all and refuses to trust them. Zero himself is now manifesting vampire traits, having been turned into vampire after he was bitten by a pure-blood vampire, Shizuka Hio, four years before.
Plot
Yuki tries to help him fight his bloodlust while also seeking to recover the memories she lost. As the series progresses, Zero's thirst for blood leads to his drinking from Yuki, by her consent, to avoid becoming a level E vampire. To stop this, Kaname gives Zero his own blood, making him a normal vampire which will prevent Zero from going insane and from needing to feed from Yuki. Eventually, it is revealed that Yuki is a pureblood vampire herself, the sister and fiancee of Kaname. To save Yuki from being killed by Rido Kuran, Kaname's uncle, her mother had sealed her memories shortly before her own death. After Yuki reawakens to her vampire nature, Rido again tries to kill her. As Kaname kills the vampire senate, Yuki fights Rido. During a fierce battle, Zero aids her in killing him, but then aims his gun at her, stating he will kill all of the pureblood vampires.
